Hypercapnia has been utilized as a stimulus to elicit modifications in cerebral blood stream (CBF). However, in many situations it has been delivered in a non-managed methodology that is usually difficult to reproduce. The purpose of this study was to study the within- and between-visit reproducibility of blood oxygen degree-dependent (Bold) signal modifications to an iso-oxic square wave alteration in end-tidal carbon dioxide partial strain (Pet CO2 ). Two 3-Tesla (3T) MRI scans were carried out on the same go to, with two square wave alterations administered per scan. The protocol was repeated on a separate go to with minimal of three days between scanning periods. Pet CO2 was altered to stimulate changes in cerebral vascular reactivity (CVR), BloodVitals SPO2 device while Pet O2 was held constant. Eleven topics (six females